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Curva que describe la relación entre la dosis, como variable independiente, y la duración del efecto del medicamento, como la variable dependiente. La pendiente de la curva es siempre positiva en contraste con la pendiente de la what is the most significant role that financial markets play tiempo-concentración. Esta curva suele corresponder a una distribución estadística normal graded dose response curve vs quantal.

Si lo que se representa es la proporción acumulada de individuos que responden graficada en contra del logaritmo de la dosis, se obtiene una curva sigmoidea. Estas curvas sigmoideas generalmente se emplean para determinar las dosis efectivas medianas, las dosis letales medianas, etc. Sinónimos: garded de dosis-respuesta cuantal, curva de dosis por ciento.

La curva obtenida es sigmoidea igual que uno de los tipos de curva de dosis-efecto cuantal. Sin embargo, la curva de dosis-efecto gradual, en vez de representar la presencia o ausencia de un determinado efecto, refleja la variación que existe en el efecto como respuesta a cambios en la dosis o, incluso, a variaciones interindividuales. En este caso, durve efectos cuantales estarían representados por la respuesta de los receptores a una determinada dosis, o por su incapacidad de responder.

Esta curva normal asume la forma sigmoidal al graficar la frecuencia cumulativa de distribución. En el panel A, la relación se establece entre la respuesta y la dosis expresada en la escala aritmética. En el panel B, la dosis se expresa en unidades logarítmicas. La curva del panel A se caracteriza por su forma de hipérbola rectangular y la curva del panel B es sigmoidea. Sinónimo: curva de dosis-efecto.

Clínicamente se caracteriza por hipotensión, contracción de la musculatura lisa y vasodilatación capilar. Aquellos resultados, también conocidos como variables y que se obtienen a partir de una observación o experimento. Por ejemplo, la temperatura corporal, la presión graded dose response curve vs quantal el quangal arterial y la mayoría de los resultados de las pruebas de laboratorio.

Es posible obtener varias categóricas policotómicas.

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