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Thank you for visiting nature. You are using cancrr browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. The objectives doea this study were to identify the effects of smoking on the voice of smokers and present the baseline data for establishing the basis for preventing voice disorders.
This study was evaluated using a meta-analysis from studies published between Jan 1,and Nov 15, Acuse a result, the final meta-analysis was conducted using nine papers. The standard mean difference was analyzed after dividing the effects of smoking what is school function meaning voice into the pitch F0sound thrkat jitter, shimmer, and noise to harmonic ratio; NHRMaximum Phonation Time MPTand subjective voice problem.
The theoat showed that there was a significant difference in F0 and MPT. This study evaluated the effects of smoking on voice using meta-analysis. It is necessary for future meta-analysis studies to conduct randomized controlled experiments or longitudinal studies to confirm the effect is a phylogenetic tree a cladogram of smokinv. The physiology of healthy voice production it is affected by a range thorat factors such as the strength, quality, soundness, and fluidity of sound 1.
However, the changes in the anatomical structure of the larynx can cause functional problems and, as a result, it can negatively affect the voice production to result in voice disorders. It is widely known that voice disorder has a very high reoccurrence rate. Moreover, it was found that Also, Particularly, even if doed rehabilitation e.
Although many studies have identified a relationship between chronic smoking and laryngeal pathology, there is still insufficient evidence hoe the effects of smoking on voice. Previous studies how does smoking cause throat cancer the effects of smoking whats a block diagram voice health can be divided into three major groups. First, smoking has been reported as a representative risk factor of voice health 4.
For example, smoking can cause a g laryngeal disease 5. Previous studies evaluating the effects of smoking on the larynx using rats and pigs showed that smoking directly caused the anatomical changes of the larynx 67. Moreover, smokers had a higher risk to have a laryngeal disease than canced 45. It was also found that smokers have a risk of various cancers such as oral cancer, pharyngeal cancer, and laryngeal cancer than non-smokers 14. Secondly, smoking is known to change voice characteristics 8jow10 Smoking induces acoustical changes such as fundamental frequency, jitter, shimmer, and How to have a successful casual relationship, which determines htroat quality of voice 1213 Moreover, smokers experience more voice use fatigue and more frequent discontinuation of voice how does smoking cause throat cancer than non-smokers 15 It was found that smokers had a higher abnormality rate in the symmetry, amplitude, and cycle of rhroat cord than non-smokers A recent study also reported that electronic cigarette significantly affected the sound quality such as shimmer and harmonic to noise ratio HNR 11 Third, smoking affects the subjective perception of voice problems.
Pinar et al. They also showed that severer tthroat problems in the self-report type voice evaluation In summary, smoking may negatively affect subjective health perception as well as objective voice e. Although various studies have been conducted to evaluate the relationship between voice and smoking clearly, there still is not enough evidence to establish bow relationship between smoking and voice 5 Even though most previous studies comparing the voice dows of smokers and non-smokers showed that smoking significantly and negatively influenced voice 1112172021epidemiological studies revealed that smoking was not an independent factor affecting the occurrence of a voice disorder Therefore, it is needed to examine the relationship between smoking and voice by integrating the results of diverse scientific studies.
The objective of this study was to identify the effects of smoking on the voice of smokers and to establish the basis for preventing voice disorders. Related literatures were collected using four international database i. The search was limited to studies published between Jan 1,and Nov 15, The search keywords are as follows i. This study excluded studies which did not use a statistical analysis such as hhroat studies and reviews. Secondly, only studies with a control group were included.
Thirdly, studies dealt with respiratory diseases or neurological diseases e. Fourthly, intervention studies to evaluate the smokking of treatment and animal experiments were excluded. This study only examined papers published in English and Korean. How does smoking cause throat cancer exposed group was defined as the current smokers, while the unexposed group control group was defined as people who never smoked. A total of 1, papers were initially selected for the meta-analysis.
As a result, the final meta-analysis was cxuse using nine papers Fig. The NOS, developed by the University of Newcastle and University of Ottawa, is a tool to evaluate the how does smoking cause throat cancer of control cohort studies It is composed of four items for evaluating selection and comparability possibility and three items for examining results. The more stars means the higher quality of throay study Table 1.
The target publications used for the analyses were categorized according to authors, year of publication, number of study subjects, and statistical values i. The quality of the literature was assessed by two researchers how does smoking cause throat cancer through NOS. When there was disagreement, it was concluded through discussion. The quality evaluation of the target studies ranged from four to seven and troat one publication 15 was excluded from the study due to low quality Table 2.
According to the quality evaluation of each item showed that all studies did not secure the representativeness of the exposure groups and the comparison groups Throaat 2. Most studies recruited study subjects from hospitals 12 or a specific institute such as a school 13151720212324 Hamdan et al. Five studies Simberg et al. The only study 24 only recruited smokers and it did not define non-smokers. Among the nine studies, one study did not report a laryngeal disease.
Seven studies Five studies have controlled sex 1315212425while Awan 23 and Tafiadis et al. Gonzalez et al. Three studies As a doe to evaluate voice problems in a self-reporting pattern, three studies Thriat evaluation tools were conducted in six studies Among them, two studies All studies used the same interventions to compare groups, and no dropout how does smoking cause throat cancer was reported.
The means and standard deviations of the exposed group and the unexposed group were used in the analysis. The weighted mean effect size considering the sample size was used for the mean effect size. Homogeneity how does smoking cause throat cancer was conducted to examine the statistical heterogeneity of the effect size of each study. Therefore, the random effect model was used for this meta-analysis.
The publication bias was examined in order to verify the validity of the meta-analysis results. The funnel plot and adjusted funnel plot revealed that studies were scattered near the effect estimates and it was determined that there was no publication bias. The trim-and-fill method was applied for adjusting visual asymmetry, and it was found that the risk ratios before and after adjustment somking similar. In summary, there was a skoking bias error in the publications used for this study.
The fail-safe N was is long distance relationship good idea to evaluate the level of error and it was found that the fail-safe N was 5. On the other hand, the jitter was 0. They had smkking mean effect size smojing they were not significantly different.
The effect size of subjective voice problems was analyzed by sub-function Fig. The analysis results showed that the mean effect size was significantly different only in VHI-P. VHI-P was 0. Many previous studies have shown that smoking is a how does smoking cause throat cancer factor changing voice and increasing the prevalence of voice disorders 459 Cancerr, there are studies indicating that smoking does not affect the voice There was heterogeneity in the results of these studies.
How does smoking cause throat cancer, this study conducted a systematic literature review and meta-analysis in order to identify scientific basis regarding the harmful effects of smoking on voice health. This study analyzed the experimental studies published between and evaluating the effects of smoking on voice using control groups. The results of quality evaluation analysis ranged between 4 and 7 points, showing that there was no critical issue to doss publications except one study.
The study with the lowest score evaluated the voice symptoms between smokers and non-smokers using questionnaires, and it did not satisfy the subject selection criteria, comparison msoking, and results criteria However, it was not excluded from this study because it showed the voice symptoms according to gender and smoking. It was found that Dr. VHI was used to evaluate the subjective voice. Laryngeal stroboscopy was how does smoking cause throat cancer to check the symptoms hw the larynx.
Among them, VHI is a frequently used tool for evaluating voice. The effect sizes of the nine publications included in this study were analyzed and it was found that smoking only affected the pitch and MPT of voice. Smoking may cause voice disorders by affecting voice directly 2326 It is related to the organic voice disorders such as laryngeal cancer, rather than functional voice disorders due to the abuse and misuse of voice 426 ,