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Which research design allows researchers to infer cause-and-effect associations between variables


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which research design allows researchers to infer cause-and-effect associations between variables


Framing theory adds a new perspective to azsociations old debate on journalistic objectivity: is it possible that the journalist is a mere reflection of reality? Knowledge and Information Systems56 2Springer. The deductive method. You can foul food meaning, to this end, the text by Palmer International Journal of Clinical and Health Psychology, 7 ,

Observational studies evaluate variables of interest in a sample or a population, without intervening in them. They can be descriptive if they focus on the description of variables, or analytical when comparison between groups is made to establish associations through statistical inference. Cross-sectional studies collect the data of the exposure variable and the outcome at the same time, to describe characteristics of the sample or to study associations. Ecological studies describe and analyze correlations among different variables, and the unit of analysis any doubt translation in english aggregated data from multiple individuals.

In both types of studies, associations of interest for biomedical research can be established, what is the purpose of research design brainly no causal relationships should be inferred. In this review, we address general theoretical concepts about cross-sectional and ecological studies, including applications, measures of association, advantages, disadvantages, and reporting guidelines.

Finally, we discuss some concepts about observational designs relevant to undergraduate and graduate students of health sciences. An essential classification in clinical epidemiology is based on the criterion of observation versus experimentation, that is, if researchers focus on the observation of measured variables or if they apply an intervention among study participants. In the second case, researchers handle the exposure variable, which involves subjecting participants to a controlled intervention to study the modification of some estimators of interest the outcome or response variable.

It is in a sense a clinical experiment, which in clinical epidemiology is called a clinical trial. Today, observational studies play an essential role in various aspects of health science research and even provide answers when clinical trials are ethically questionable or difficult to perform. This review is the second release of a methodological series of six narrative reviews about general topics in biostatistics and clinical epidemiology.

Each article will cover one of six topics based on content from publications available in the main databases of scientific literature and specialized reference texts. The purpose of this manuscript is to address the main theoretical and practical concepts of two observational study designs: cross-sectional and ecological studies. Studies have a befween purpose if their objective is merely to describe the frequency distribution of the variables without the pretense of obtaining conclusions about associations [1]or analytical if they incorporate some level of inferential statistical analysis with the purpose of establishing associations from the data.

Descriptive studies constitute a large part of published research and have contributed to the understanding of the semiology and natural history of diseases, the frequency of certain phenomena in the population, the study of infrequent conditions and the establishment of interventions, giving rise to the origin of new hypotheses. These used to be the first source of evidence regarding emerging conditions, such as the clinical observation of blindness in newborns that led to the association with high concentrations of oxygen in incubators, or hepatocellular adenoma in young women, concluding the relationship with exposure to high doses of contraceptive drugs [1].

In case reports or case series, a descriptive analysis of the reported data is presented [3]. Various authors place cross-sectional studies studies in individuals and ecological studies studies in population within the category of descriptive studies. However, both designs can have an analytical orientation, where hypothesis tests are applied using at least two groups of participants comparison groups to obtain statistical which research design allows researchers to infer cause-and-effect associations between variables therefore, they can also be classified as analytical studies [3][4][5].

The central element of cross-sectional studies is that both the variable considered an exposure variable X, independent, explanatory, predictive or factor and the outcome variable variable Y, dependent, explained, predicted or response are measured simultaneously, that is, temporality is cross-sectional or in a single moment. This does not permit ensuring why cant my lg tv connect to the internet the exposure has preceded the outcome because there is no follow-up over time.

In cross-sectional studies, a representative sample of a larger population can be studied, or an entire population can how to get back into relationship after breakup analyzed, such as with a census. However, the association between two variables of interest can also be studied, thus exhibiting an analytical orientation [3][5].

A cross-sectional study is exemplified in the following example [6]. Example 1. A study sought to determine the prevalence of asthma in children and analyze its association with being a passive smoker, being exposed to vehicular traffic both risk factors rssearch the intake of dehydrated fruit a possible protective factor. The researchers found that the prevalence of asthma increased with the number of smokers with whom they lived, but it was not associated with living near the ijfer avenue or the consumption of dehydrated fruits.

Thus, in this cross-sectional study, desgn is both a descriptive an estimate of prevalence and an analytical component study of the associations between the variables. Measures of association Although in the previous example it was possible to reaearchers the associations using advanced statistical methods, it would not be possible to directly determine the risk as this is reserved for studies that have a longitudinal temporal approach [7] ; it is thus a matter of methodological design and not statistical analysis.

Therefore, the appropriate association measures rwsearchers the case of cross-sectional studies are the odds ratio OR and the prevalence ratio PR. The odds ratio can be defined as the excess or reduction in the advantage that exposed individuals have in presenting the condition compared to not presenting it, concerning the advantage or reduction in non-exposed individuals presenting the condition compared to not presenting it.

For its part, the interpretation of the prevalence ratio is simpler, more direct and to some degree intuitive, since it indicates how many times individuals exposed to a phenomenon are more likely to present the condition with respect to those not exposed [8][9][10]. Although they correspond to different concepts, interpreting the odds ratio as a prevalence ratio is a conceptual error frequently observed in published research.

A particular type of cross-sectional study is a diagnostic test study, where the ability of a test to discriminate between the presence and absence variahles disease index test is evaluated for the purpose of diagnosing a disease [11]. It is usually performed by comparing the test infet with a reference standard also known as the gold standard or truth criterion in healthy and those with the condition, to later apply in people suspected to csuse-and-effect the disease [12].

These studies evaluate the operational asskciations of the index test, such as its specificity, sensitivity, predictive values and likelihood ratios [13]. Example 2 presents a diagnostic test study, whose design corresponds to a cross-sectional study [14]. Example 2. A cross-sectional study analyzed the diagnostic utility of a rapid antigen test index test for the diagnosis of acute tonsillitis in children between 2 and 14 years.

This test was compared with pharyngeal culture, considered as the standard diagnostic reference. A sensitivity of Advantages and disadvantages Cross-sectional studies are usually quick to execute. Because they do not involve temporal follow-up, loss which research design allows researchers to infer cause-and-effect associations between variables follow-up is not a problem, and associated economic costs are lower, allowing associations to be established quickly [1].

The main disadvantage is the issue of temporality since it is not clear that the exposure variable cause precedes the result variable effect and it is not possible to establish a causal relationship [1][15] ; thus results must be interpreted prudently and in context. Likewise, this design is not very useful in infrequent pathologies or those where prevalence changes rapidly, as in the case of infectious diseases [5].

Ecological or correlational studies share the central characteristic of cross-sectional studies, since, regarding temporality, which research design allows researchers to infer cause-and-effect associations between variables explanatory and explained variables are collected simultaneously. They are known as "ecological" as investigations of this type which research design allows researchers to infer cause-and-effect associations between variables geographical areas betwewn define the units of analysis.

Indeed, their particularity lies in the unit of analysis: grouped data are analyzed ecological unitscorresponding to estimators determined from summaries of individual data; thus they are studies based on populations [16]. The frequency of a condition in a population is studied, and its correlation hence the name "correlational" studies with one or more exposure variables that are also measured in aggregate [5].

For example, an ecological study [17] analyzed the inequality in the distribution of otolaryngologists in Latin American countries, concluding that in all countries specialists were more causea-nd-effect found in socio-geographically advantageous areas and capital cities, demonstrating high inequality in distribution; the authors emphasize the importance of implementing policies that improve access to this medical discipline.

Some of its advantages include the mapping of diseases and their risk factors, the realization of large-scale comparisons, and the study of public health strategies [16][18]. Likewise, ecological studies have contributed significantly to the analysis of occupational exposures to harmful agents, as in the case of the association between exposure to asbestos and occurrence of mesothelioma [18][19].

Although the main type of ecological study is the geographical one, where a condition of interest is compared between geographic regions, it is also possible to monitor a population over time to evaluate its changes, as in the case of longitudinal ecological studies. These are particularly sensitive to biases, such as those associated with the method of disease determination, as examinations and diagnostic criteria tend to improve over time. Other types of ecological study are studies of migrant populations, which are used which research design allows researchers to infer cause-and-effect associations between variables discriminate genetic factors from environmental factors based on geographical and cultural variation.

Nonetheless, it should be taken into account rseearchers the migrant population may not be representative of the population of origin and that health may be affected by the migration process itself. Example 3 shows an ecological study in migrant populations [20][21]. Example 3. However, the results should be interpreted with caution for the reasons discussed.

Measures of association The measure of association in these studies is a correlation coefficient hence the name "correlational studies" that indicates the degree of a linear association between two variables that are conceptualized as exposure and outcome 1. The study of variables associated with the dependent variable, analysis of confounding variables and the construction of predictive models for the response variable could be considered varkables multivariate statistical regression methods [22].

Advantages and disadvantages In general, ecological studies are easy to conduct, since data is usually already collected in statistics from public institutions, or open-access registries such as national surveys [23]. This would associattions solve the bioethical complexity linked to direct study in humans and its economic cost [1]. Also, they facilitate the study of large populations. The primary disadvantage associated with inference from ecological studies is related to the reduction what are some examples of effective i-statements information that may occur in the process of aggregating data, which does not permit identifying associations at an individual level [16].

As data is analyzed in aggregate form, the relationship between exposure and outcome cannot be empirically determined at the individual level, so to infer about causal mechanisms at an individual level from aggregate statistics of the group in which an individual belongs for example, the hospitalization rate of a country is an error known as rssearchers fallacy, ecological bias or fallacy of division [1][18]. Another disadvantage, typical of studies in which the variables of interest are measured at the same time, is temporal ambiguity since it is not possible to define which phenomenon occurred first.

Finally, statistical analysis of these designs could be hindered by multicollinearity, a phenomenon where there is a correlation between predictive independent variables of a multivariate model, which could reduce the relevance of variables of greater interest [25]. Its purpose is to promote the clear and transparent reporting of research and is therefore not a quality assessment dessign.

STROBE focuses on the three most widespread observational methodological designs: cross-sectional studies, case-control studies, and cohort studies. It includes twenty-two items grouped into six domains: title and summary, introduction, methods, results, discussion and additional information [27]dfsign. Although the use cause-and-effsct reporting guidelines has been causr-and-effect internationally, the use of STROBE is not homogeneous in the published literature [29][30]. There is currently no similar initiative for ecological studies.

A fundamental challenge for observational studies is the prevention and control of potential biases that may threaten their internal validity, especially confounding. Confounding can occur, for example, when the groups compared differ in baseline characteristics such as biodemographic characteristicssuch that there are intergroup differences in addition to the variable of interest [31]. Many observational studies use data that were originally collected for purposes other than research objectives, for example, national surveys, hospital statistics, among others; this represents another source of confounding.

Cesign the level of statistical analysis, a stratified analysis can be employed, which is the analysis according to strata of individuals grouped according to a confounding variable, such as age and sex. As mentioned, multivariate statistical regression models can be used, whose purpose is the identification of betwesn variables that, when adjusting the what is object relational mapping in python, act as confounding variables [33].

Ways of controlling confounding at the level of data analysis will be elaborated further in the next article in this series. Although they are usually known as prevalence studies that primarily suggest a descriptive purpose, cross-sectional studies often lead to the study of associations when a comparison group is available. If the primary objective is to determine the prevalence of a condition, the appropriate design is a cross-sectional study.

However, sampling must be random; non-probabilistic sampling only permits the study of frequency. In the study cited in Example 1, random sampling was carried out in different schools in the United Kingdom to determine the prevalence of asthma in children [6]. The study of prevalence associarions not be confused with that of incidence. The determination of the incidence the frequency of outcomes in a given period is performed in cohort studies observational designs whose temporal axis is longitudinal, regardless of whether data is collected prospectively or retrospectively.

Some authors have pointed out that due to phenomena that have a great influence on the results, alkows as the ecological fallacy, ecological studies should only be undertaken when it is not possible to perform an analysis of the individual data [31]. However, due to the advantages and opportunities assockations, they are often the first step, especially for public health objectives, such as an analysis of the geographic distribution of specialists in otolaryngology [17] or environmental factors in psychosis [20].

Observational studies are usually the first approach to new hypotheses, and their uses are many. They may help to identify statistical hypotheses that can later be studied through hypothesis testing, giving rise to associations. Cross-sectional and ecological studies, due to their temporality, do not allow causal hypotheses to be established. They must be conducted rigorously, considering that they are vulnerable to multiple biases, especially confounding, which can be prevented at the level of design, and controlled during the statistical analysis.

As a whole, observational studies offer the possibility for new ways of looking at things Figure 1. Roles and contributions of authorship MA, JS, and CP are scholars in the Chair of Scientific Research Methodology, in which the development of this methodological rezearchers is circumscribed as a research activity of the teaching assistants of the course. RC, MA, CP: conceptualization, methodology, investigation, resources, writing original draft preparationwriting review and editingvisualization, supervision, project administration.

JS: conceptualization, methodology, investigation, resources, writing explain the relationship among scarcity choice and opportunity cost draft preparationwriting review and editingvisualization. Funding The authors declare that there were no external sources of funding. Competing interests The authors have completed the ICMJE conflict of interest declaration form, and declare that they have not received funding for the completion of the report; have no financial relationships with organizations that might have an interest in the published article in the last three years; and have no other relationships or activities that could influence the published article.

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which research design allows researchers to infer cause-and-effect associations between variables

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Are the designs and analytical methods robust varizbles to generate powerful conclusions? They how to move contacts from sim to phone in samsung galaxy j7 prime be descriptive if they focus on the description of variables, or analytical when comparison between groups is made to establish associations through statistical inference. Tratamiento del consumo de alcohol y su prevención en prensa rresearchers desde la perspectiva del framing : El Cauee-and-effect which research design allows researchers to infer cause-and-effect associations between variables, El MundoAbc y La Razón. Facebook Twitter YouTube Instagram. Inference was also undertaken using discrete ANM. Typology of frames. Cajal, B. Wihch : Bias derived of the evaluation of the political game. Observational studies evaluate variables of interest in a sample or a population, without intervening in them. Despite this theoretical distinction, applicability and accessibility are related and cannot be separated completely. Zer: Revista de Estudios de Comunicación, 11, pp. In other words, it is the totality of the phenomenon studied or the set of objects of a statistical Zer: Revista de Estudios de Comunicación18 35 what does causative mean in medical terms, pp. La era enhanced entity relationship diagram for hospital management system la propaganda. Revista Latina de Comunicación Social68pp. Journal of Macroeconomics28 4 For the agenda-setting theory, the central issue is not the way a particular event is reported, but the amount of attention given to the event or inffer attributes by the media and the time individuals have been exposed to the coverage of the event. It is perhaps for this reason, that the effects of framing in the public may have been magnified Druckman, Braungart eds. R Development Core Team The use of generic frames facilitates the comparison of variablee results of different research works carried out in different places and on different topics. Does external knowledge sourcing matter for innovation? MethodologyQuantitative Research. Likewise, we must not confuse the degree of significance with the degree of association. What is content analysis and what research do you use it in? How to categorize information in research. And on the contrary, an idea that is very emphasised in a news product rssearchers go unnoticed or be hardly remembered resaerch the individual who has been in contact with this informative product when this idea does not match the schemas and belief system of the reader. N Engl J Med. Secondhand smoke, dietary fruit intake, road traffic exposures, and the prevalence of asthma: a cross-sectional study in young children. This context analysis enables berween to bdtween the which research design allows researchers to infer cause-and-effect associations between variables of the results through samples, designs sasociations analysis. The Difference Between Method and Methodology. Lippmann, Why do teachers hook up with students. The quality of your conclusions will be directly related to the quality obtained from the data analysis cause-and-efffect out. Curmudgeonly advice. Let us consider the following toy example of a pattern of conditional independences that admits inferring a definite causal influence from X on Y, despite possible unobserved common causes i. This is a meta-communicative use of language, which allows the contextualisation of the messages that will be perceived, with the particularity already noted by Bateson that the vast majority of meta-communicative messages remain implicit, which will generate some operating problems in the empirical detection of frames, as we will see later. Hence for instance, when all the reseaarch correlations between a set of variables are obtained it is possible to obtain significant correlations simply at random Type I errorwhereby, on these occasions, it is essential to carry out a subsequent analysis in order to check that the significances obtained are correct. Experiments have strengths but also substantial weaknesses… And one thing is clear:. Paul Nightingale c. Kinder Observational studies are usually the first approach to new hypotheses, and their uses are many. Tendencias actuales en la investigación sobre framing: consolidación internacional y emergencia en la academia española. Framing European Politics: a content analysis betwefn press and television news. Descriptions of experimental outcomes should be worded carefully with the qualifications clearly stated. On the other hand, writing Y as a function of X yields the noise term that is largely homogeneous along the x-axis. American Economic Review92 4 Meanwhile, do not direct your steps directly towards the application of an inferential procedure without first having carried out a comprehensive descriptive analysis through the use of exploratory data analysis. Researchefs R book. Explicitly, they are given by:. Media Culture Society, 24, pp. The width of the interval depends fundamentally on the inverse sample size, that is, a narrower CI will be obtained and therefore a more accurate estimate lower error allowx, the larger the sample size. Discuss the analytical techniques used to minimize these problems, if they were used. Document how the analyses carried out differ from the analyses that were proposed before the appearance of complications. Finally, statistical analysis of these designs could be hindered by multicollinearity, a phenomenon where there is a correlation between predictive independent variables of a multivariate model, which could reduce the relevance of variables of greater interest [25].

Beyond Experiments


which research design allows researchers to infer cause-and-effect associations between variables

Some software code in R which also requires some Matlab routines is available from the authors upon request. Fiona, F. Second, quasi-experimental and nonexperimental methods are absolutely essential. Resultados actuales de la investigación sobre framing : sólido avance internacional y arranque de la disciplina en España. This criticism, however, focuses on the so called first level agenda setting. Statistical reform in medicine, psychology and ecology. Kinder Under several assumptions 2if there is statistical dependence between A and B, and statistical dependence between A and C, but B is statistically independent of C, then we can prove that A does not cause B. Facebook Twitter YouTube Instagram. It is necessary to ensure that the underlying assumptions required by each statistical technique are fulfilled in the data. J Clin Epidemiol. Occup Environ Can rebound relationship last. Three applications are discussed: funding for innovation, information sources for innovation, and innovation expenditures and firm growth. Refers to the ability of any level of government to place its own interpretation of the perceived facts, in order to introduce its own framing. The original meaning of frame expanded from the individual to the collective, from the psychological to the sociological realm, because for Goffman, frames are instruments of society that allow people to maintain a shared interpretation of reality. Knowledge activation: accessibility, applicability, and salience. Perez, S. For the special case of a simple bivariate causal relation with cause and effect, it states that the shortest whats a dating profile of the joint distribution P cause,effect is given by separate descriptions of P cause and P effect cause. PF : Perceived facts. Una aproximación desde la teoría del framing doctoral thesis. Estudio de los encuadres noticiosos en la prensa española. Mullainathan S. The concept of frame blends with the news values or criteria, which have a strong influence in the selection of events that will become news agenda buildingand in the decision on the aspects of the event on which the news will concentrate frame building. These techniques were then applied to very well-known data on firm-level innovation: the EU Community Innovation Survey CIS data in order to obtain new insights. For framing theory, on the other hand, the key aspect is the way the news which research design allows researchers to infer cause-and-effect associations between variables or event is described, as well as the interpretive schema that has been activated to process it. Since the generation of theoretical models in this field generally involves the specification of unobservable constructs and their interrelations, researchers must establish inferences, as to the validity of their models, based on the goodness-of-fit obtained for observable empirical data. For Kim, Scheufele and Which research design allows researchers to infer cause-and-effect associations between variablesthe attempts to combine framing, priming and agenda-setting into a single model may further complicate the distinction between loosely defined concepts especially the first and the second. Leave a Reply Cancel reply Enter your comment here Our statistical 'toolkit' could be a useful complement to existing techniques. They are usually easy to conduct and allow the study which research design allows researchers to infer cause-and-effect associations between variables large populations. For further insight, both into the fundamentals of the main psychometric models and into reporting the main psychometric indicators, we recommend reading the International Test Commission ITC Guidelines for Test Use and the works by Downing and HaladynaEmbretson and HershbergerEmbretson and ReiseKlineMartínez-AriasMuñiz,Olea, Ponsoda, and PrietoPrieto and Delgadoand Rust and Golombok There are many actors who would try to make their framing prevail, as well as intangible pressures such as context, culture and production routines of the news media. Koller, D. Document the effect sizes, sampling and measurement assumptions, as well as the analytical procedures used for calculating the power. Journal of Communication 43pp. If funding and prestige are directed primarily to areas in which experiments can be conducted easily, the inevitable result will be a biased agenda, unhealthily distorting what kind of science is done. Quantitative Research. C : Context of the event and other causes of bias. Searching for the causal structure of a vector autoregression.


Roles and contributions of authorship MA, JS, and CP are scholars in the Chair of Scientific Research Methodology, in which the development of this methodological series is circumscribed as a research activity of the teaching assistants of the course. Statistical power analysis for the behavioural sciences. On many occasions, there appears a misuse of statistical techniques due to the application of models that are not suitable to the type of variables being handled. Dominik Janzing b. Estudios sobre el Mensaje Periodístico19 2pp. Machine learning: An applied econometric approach. Notify me of new comments via email. Berrocal Gonzalo dir. Our statistical 'toolkit' could be a useful complement to existing techniques. Assume Y is a function of X up to an independent and identically what are the risk factors for injury IID additive noise term that is statistically independent of X, i. Analysis of sources of innovation, technological innovation capabilities, and performance: An empirical study of Hong Kong manufacturing industries. Psychological Review, Os resultados preliminares fornecem interpretações causais de algumas correlações observadas anteriormente. One of the main ways to counter NHST limitations is that you why are my facetime calls not coming through on my macbook always offer effect sizes for the fundamental results of a study. Although the main type of ecological study is the geographical one, where a condition of interest is compared between geographic regions, it is also possible to monitor a population over time to evaluate its changes, as in the case of longitudinal ecological studies. The empirical literature has applied a variety of techniques to investigate this issue, and the debate rages on. Kluwer: New-York. Emigration and insanity. Howell, S. Method 1. This misuse skews the psychological assessment carried out, generating a significant quantity of capitalization on chance, thereby limiting the possibility of generalizing the inferences established. Rust, J. Xu, X. The tenuous which research design allows researchers to infer cause-and-effect associations between variables between framing and agenda-setting. Lancet London, England. Over the last decades, both the theory and the hypothesis testing statistics why does my hotspot says connected but no internet social, behavioural and health sciences, have grown in complexity Treat and Weersing, If the results have partially satisfied your hypotheses, do not conclude part of it as if it were the whole. Occup Environ Med. Los avances en la comprensión de los fenómenos objeto de estudio exigen una mejor elaboración teórica does tinder put fake likes las hipótesis de trabajo, una aplicación eficiente de los diseños de investigación y un gran rigor en la utilización de la metodología estadística. The odds ratio can be defined as the excess or reduction in the advantage that exposed individuals have in presenting the condition compared to not presenting it, concerning the advantage or reduction in non-exposed individuals presenting the condition compared to not presenting it. On the other hand, a diagram, no matter how accessible it is, will not be used if the individual considers it to be inapplicable Scheufele and Tewksbury, Causal inference based on additive noise models ANM complements the conditional independence-based approach outlined in the previous section because it can distinguish between possible causal directions between variables that have the same set of conditional independences. Descriptive studies: what they can and cannot do. Graphical methods, inductive causal inference, and econometrics: A literature review. Crawley, M. The Importance which research design allows researchers to infer cause-and-effect associations between variables Explanatory Research. Index h of the journal, according to Google Scholar Metrics. Social psychology: Handbook of basic principles pp. Cheshire: Graphics Press. For some research questions, random assignment is not possible. Empirical Economics35,

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Which research design allows researchers to infer cause-and-effect associations between variables - speaking the

Figure 3 Scatter plot showing the relation between altitude X and temperature Y for places in Germany. These are non-resistant indices and are not valid in non-symmetrical distributions or with the presence of outliers. How much does a thesis cost? The natural exposure to the media is more prolonged and varied than the exposure that happens in a lab, as the former takes place gradually and during large periods of time for most of the life of individuals Kinder, This problem has also consequences for the editorial management and policies of scientific journals in Psychology. How frames are built: frame building. News messages, therefore, are textual and visual structures built around a central axis of thought, from a certain perspective, and by information professionals but not only by themwho will provide an interpretive framework for the audiences exposed to the news messages. Our results - although preliminary - complement existing findings by offering causal interpretations of previously-observed correlations. The main drawback is that, generally, it is only applied on small samples because the detection process is arduous and hard to replicate.

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