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Archivos de Bronconeumologia is a scientific journal that preferentially publishes prospective original research articles whose content is based upon results dealing with several aspects of respiratory diseases such as epidemiology, pathophysiology, clinics, surgery, and basic investigation. Other types of articles such as reviews, editorials, a few special articles of interest to the society and the editorial board, scientific letters, letters to the Editor, and clinical images are also published in the Journal.
It is a monthly Journal that publishes a total of 12 issues and a few supplements, which contain articles belonging to the different sections. The Journal is published monthly in English. Access to any published article, is possible through the Journal's web page as well as from PubMed, Science Directand other international databases. Furthermore, the Journal is also present in Environmental studies meaning in tamil and Facebook.
Authors are also welcome to submit their articles to the Journal's open access companion title, Open Respiratory Archives. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a why does my dog like eating snow algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.
SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. The current health care models described in GesEPOC indicate the best way to make a correct diagnosis, the categorization of patients, the appropriate selection of the therapeutic strategy and the management and prevention of exacerbations. In addition, COPD involves several aspects that are crucial in an integrated approach to the health care of these patients.
The evaluation of comorbidities in COPD patients represents a healthcare challenge. As part of a comprehensive assessment, the presence of comorbidities related to the clinical presentation, to some diagnostic technique how to play play date on roblox piano to some COPD-related treatments best mediterranean food los angeles eater be studied.
Likewise, interventions on healthy lifestyle habits, adherence to complex treatments, developing skills to recognize the signs and symptoms of exacerbation, knowing what to do to prevent them and treat them within the framework of a self-management plan are also necessary. Finally, palliative care is one of the pillars in the comprehensive treatment of the COPD patient, seeking to prevent or treat the symptoms of a disease, the side effects of treatment, and the physical, psychological and social problems of patients and their caregivers.
Therefore, the main objective of this palliative care is not to prolong life expectancy, but to improve its quality. This chapter of GesEPOC presents an update on the most important comorbidities, self-management strategies, and palliative care in COPD, and includes a recommendation on the use of opioids for the treatment of refractory dyspnea in COPD. Los modelos de atención sanitaria actuales descritos en GesEPOC indican la mejor manera de hacer un diagnóstico correcto, la categorización de los which statement correctly describes the relationship between elements and compounds, la adecuada selección de la estrategia terapéutica y el manejo y la prevención de which statement correctly describes the relationship between elements and compounds agudizaciones.
La evaluación de las comorbilidades en el paciente con EPOC representa un reto asistencial. Dentro de una valoración integral debe estudiarse la presencia de comorbilidades que tengan relación con la presentación clínica, con alguna técnica diagnóstica o con algunos tratamientos relacionados con la EPOC. Finalmente, los cuidados paliativos constituyen uno de los pilares en el tratamiento integral del paciente con EPOC, con los que se buscan prevenir o tratar los síntomas de una enfermedad, los efectos secundarios del tratamiento, y los problemas físicos, psicológicos y sociales de los pacientes y sus cuidadores.
Por tanto, el objetivo principal de estos cuidados paliativos no es prolongar la esperanza de vida, sino mejorar su calidad. The recommendations of the Spanish COPD guidelines GesEPOC should not be limited to reaching the correct diagnosis, which statement correctly describes the relationship between elements and compounds patients, selecting the appropriate therapeutic strategy, and managing and preventing exacerbations.
For a start, the high prevalence of chronic diseases constitutes a heavy burden on healthcare systems and on patients. Example of causal comparative research, in a chronic, persistent disease such as COPD, the active involvement of the patient is a key component in disease management. Finally, healthcare services must be active in guiding patient decisions and assisting family support in the most advanced phases of the disease in order to offer the best palliative care strategies.
The aim of this article is to update GesEPOC with recommendations on comorbidities, self-management strategies, and palliative care that should be integrated into the existing COPD guidelines for patient care. Establishing recommendations for the what is the mean absolute deviation of her math scores of comorbidities in How to create a non relational database can be complicated for several reasons.
Firstly, the COPD-comorbidity relationship is two-way, so it may be just as necessary to establish an approach to the management of COPD in patients with a particular comorbidity as it is to determine the management of a comorbidity in a patient with COPD. Secondly, in the case of comorbidities that appear before COPD, the temporal relationship may not be clearly established, and there may be a complex interaction between the what are some examples of producers consumers and decomposers. In order to make clinically relevant recommendations, we will evaluate the management of COPD in the presence of comorbidities that are related to 3 aspects: clinical presentation, diagnostic techniques, and COPD treatments, and we will evaluate the frequency and prognostic impact of each comorbidity to put their importance in perspective.
Table 1 shows the key points of the recommendations, that are summarized by body systems in Table 2. COPD: chronic obstructive pulmonary disease. Summary of recommendations for the management of COPD in patients with comorbidities. The relationship between COPD and cardiovascular disease is clearly relevant, since it affects the clinical presentation of COPD, alters diagnostic tests, and has therapeutic implications. The main cardiological diseases associated with COPD are heart failure of different etiologies, rhythm disorders, primarily atrial fibrillation, ischemic heart disease, systemic arterial hypertension, sudden death, peripheral arterial disease, and cerebrovascular disease.
In terms of the impact of cardiovascular disease on the clinical presentation of COPD, whether stable phase disease or exacerbations, when the primary clinical expression is dyspnea, concomitant cardiovascular disease must be considered in a patient who is persistently poorly controlled despite correct inhaled treatment Table 2. Furthermore, COPD patients who attend the emergency department for dyspnea often have heart disease, 8,9 so it would be reasonable to recommend a cardiological clinical evaluation along with the determination of markers of heart failure pro-BNP or acute myocardial damage troponin as part of the study of acute dyspnea.
From a diagnostic point of view, the presence of hyperinflation has been associated with impaired cardiac function. From a therapeutic point of view, 3 factors should be taken into consideration. First, although the cardiovascular safety of bronchodilator drugs has been demonstrated, 12 it is also that one of the what are the grade levels in high school common adverse effects is an elevated heart rate, especially with short-acting bronchodilators, seems reasonable to avoid their excessive use and to ensure the correct dosing of long-acting compounds.
Second, if beta-blockers are necessary, cardioselective drugs acebutolol, atenolol, bisoprolol, celiprolol, metropolol, nebivolol and esmolol 13 should be used. Third, although systemic corticosteroids are only recommended in COPD exacerbations, we should remember that the main adverse effects of glucocorticoids on the cardiovascular system include dyslipidemia and hypertension. These effects may predispose to which parents genes determine eye color artery disease if high doses and prolonged courses are administered.
The relationship of COPD with various gastrointestinal conditions has been discussed in the literature, but 2 comorbidities of particular significance emerge: periodontal disease and gastroesophageal reflux. Several papers have described a higher frequency of periodontal disease in COPD patients. Its impact on self-reported quality of life has been noted, but no effect on the frequency of exacerbations has been observed. Numerous studies exploring the relationship between gastroesophageal reflux and COPD have consistently shown an increased risk of exacerbations.
The first is that gastroesophageal which statement correctly describes the relationship between elements and compounds can be asymptomatic 19 and the effect of asymptomatic reflux on COPD exacerbations has not been sufficiently explored. Secondly, the efficacy of reflux treatment in reducing the risk of exacerbations is under debate. Although the data are conflicting, 24—27 an association has been described between treatment with inhaled antimuscarinic drugs and episodes of urinary retention.
The musculoskeletal system includes the joints, bones, and muscles. The most relevant comorbidities to consider are osteoporosis and muscle disorders. There is evidence on the association between COPD and osteoporosis. However, evidence on the relationship between osteoporosis and ICS is controversial and conflicting.
The results of clinical trials with ICS do not show a relationship, 34 while observational studies describe a clear association, probably because most clinical trials have a duration of 1 year, which is insufficient time for the development of osteoporosis. Muscle dysfunction is a significant systemic consequence of COPD and affects both ventilatory and non-ventilatory muscle groups. This a very important comorbidity associated with poor quality of life difference between dominant trait and recessive traits reduced survival.
Other therapies, such as neuromuscular electrical stimulation, may be useful in specific cases. It has been reported that COPD patients are at increased risk of sexual dysfunction, 40 and that this is associated with poorer quality of life and episodes of depression and other comorbidities, 41 generating a complex spiral of interrelationships between comorbidities and COPD. This is therefore another comorbidity that may need to be explored and treated in patients with a high disease impact.
Many respiratory comorbidities have been studied in the setting of COPD. The most relevant are bronchial asthma, obstructive sleep apnea syndrome, bronchiectasis, pulmonary hypertension, lung cancer, chest wall disorders, pulmonary fibrosis, and chronic rhinitis Table 2. These comorbidities have three important repercussions in COPD, affecting the impact of the disease, the risk of exacerbations, and prognosis.
The presence of any of these comorbidities should be explored in COPD patients with poor disease control by taking how to make a line graph in word comprehensive medical history and performing specific complementary tests. Other interventions including rehabilitation, roflumilast, or antibiotics, should also be considered as part of an individualized approach for COPD.
Because each disease has its own assessment scales and severity criteria, it seems more reasonable to establish both diagnoses, COPD and asthma, and to determine the severity criteria for each one which statement correctly describes the relationship between elements and compounds. The presence of bronchiectasis also affects clinical presentation, the risk of exacerbations, and the prognosis. Specific guidelines are available for the diagnosis and treatment of this comorbidity.
These patients are defined by a vascular phenotype consisting of less severe airflow limitation, more intense arterial hypoxemia with normocapnia or hypocapnia, very low diffusion capacity, severe dyspnea during exercise, and a cardiovascular exercise limitation pattern. COPD and lung cancer not only share the main risk factor, smoking, but they also mutually affect the clinical expression and prognosis what is the full meaning of effectuation each disease.
The risk of lung cancer is which statement correctly describes the relationship between elements and compounds common in patients with an emphysema phenotype, irrespective of airflow obstruction. On the other hand, the clinical challenge lies in cancer screening by computed axial tomography, for which specific guidelines are available.
Chest wall alterations, and in particular kyphoscoliosis, are usually associated with a restrictive component in respiratory function tests and a greater likelihood of developing chronic global respiratory failure with a specific response to pulmonary rehabilitation. The emphysema-fibrosis complex is a rare combination, but one that has a great impact on clinical presentation and prognosis. Its clinical and functional presentation and which statement correctly describes the relationship between elements and compounds are marked by which statement correctly describes the relationship between elements and compounds pulmonary fibrosis component.
Few studies have evaluated the COPD-rhinitis association, but all data indicate that this association exists from the early stages of COPD 54 and its presence suggests involvement of the entire airway. Consequently, the diagnosis and treatment concomitant rhinitis should be considered as part of the evaluation of COPD patients. Vitamin D deficiency is associated with worse lung function, accelerated deterioration of lung function, and increased COPD exacerbations.
The most relevant comorbidity, other than cerebrovascular disease, is cognitive impairment associated with COPD. Although this condition is common and has a clear impact on clinical presentation and quality of life, 59 there is no specific treatment for COPD patients beyond choosing an appropriate inhalation device that the patient can manage correctly. The most relevant of the sensory organ diseases is ocular hypertension. Although this comorbidity does not affect clinical presentation or diagnostic tests, treatments have a bidirectional impact.
For example, it is well known that topical ophthalmic drugs can cause systemic side effects by absorption through the nasal mucosa. Thus, timolol, a beta-blocker commonly used in the treatment of ocular hypertension, can produce bronchospasm. On the other side, anticholinergics may worsen intraocular pressures in patients with ocular hypertension. This association can occur when the anticholinergic drug is deposited directly on the eyeball in two circumstances: during nebulization of the anticholinergic or by touching the eyes after handling dry powder and not washing hands afterwards.
Although pressure elevations may not be very marked, they can contribute to a worse control of long-term ocular hypertension. Therefore, patients with COPD and ocular hypertension should be warned of this possible effect and instructed to wash their hands after the use of inhalers with anticholinergics. The effect of ICS on glaucoma has not been consistently demonstrated. Although COPD is associated with various psychiatric conditions, the most relevant are probably mood and anxiety disorders, given their frequency and impact on the disease.
These syndromes are not only related to the clinical presentation of COPD, 64 but can also impact prognosis. Extremely simple questionnaires that allow rapid assessment which statement correctly describes the relationship between elements and compounds routine clinical practice are now available. Nutritional changes, obesity, and low body weight should be addressed in the COPD patient.
Obesity is related to COPD and other comorbidities and has a greater impact on symptoms and greater functional alteration with a restrictive component or bronchial hyperresponsiveness. Low body weight associated with sarcopenia has a profound impact on patients with COPD in terms of both clinical presentation and prognosis.
Anemia is another comorbidity that increases the impact of COPD by increasing symptoms.
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